Zhefeng Guo, Ph.D.
he/him/his
2003 Ph.D. in Biochemistry, University of California, Los Angeles
1998 M.S. in Biochemistry, Peking University
1995 B.S. in Microbiology, Shandong University
Dr. Zhefeng Guo is a structural biologist and biochemist who joined the UCLA School of Medicine faculty in 2008. During his doctoral studies, he focused on developing electron paramagnetic resonance (EPR) methods to study protein structure, dynamics, and folding in Wayne Hubbell’s laboratory. In 2004, Dr. Guo joined David Eisenberg’s research group for postdoc training, working on the structural characterization of amyloid fibrils using the approaches of protein engineering and X-ray crystallography. His laboratory is currently investigating the structure and fibrillization mechanism of amyloid fibrils related to a wide range of human disorders such as Alzheimer’s, Parkinson’s and prion diseases, with the goal of developing molecular diagnostics and therapeutics for amyloid diseases.
Current Lab Members
Undergraduate Research Assistants
Anna Li
(she/her/hers)
Third Year
Microbiology, Immunology, & Molecular Genetics
Current Project(s):
DHFR, Tau
Diana Portugal
(she/her/hers)
Fourth Year
Molecular, Cell, &
Developmental Biology
Current Project(s):
Screening
Zili Qiu
(he/him/his)
Third Year
Molecular, Cell, &
Developmental Biology
Current Project(s):
T4L, TMEM106B
Anson Cheung
(he/him/his)
Fourth Year
Biochemistry
Current Project(s):
DHFR, Tau
Christine Ma
(she/her/hers)
Third Year
Molecular, Cell, &
Developmental Biology
(Specialization in Computing)
Current Project(s):
Screening, T4L
Ellie Hilgert
(she/her/hers)
Second Year
Neuroscience
Current Project(s):
T4L, TMEM106B
Divya Hebber
(she/her/hers)
Second Year
Molecular, Cell, & Developmental Biology
Current Project(s):
DHFR
Kestrel Locke
(she/her/hers)
Alumni
Psychology
Current Project(s):
Alpha-synuclein, Tau
Josh Moore
(he/him/his)
Third Year
Microbiology, Immunology, & Molecular Genetics
Current Project(s):
Fyn
Caitlin Tang
(she/her/hers)
Second Year
Computational and Systems Biology
Current Project(s):
ADNI
Eliot Mark
(she/her/hers)
Second Year
Psychology
Current Project(s):
Screening
Former Lab Members
Undergraduate Research Assistants
• Wenshu (Claire) Zhang
• Allison Yoon
• Ani Oganesyan
• Chloe Wang
• Alex Sun
• James Zhen
• Brandon Dashtizad
• Katrina Cheng
• Andrew Tran
• Hyein (Haily) Kil
• Terri Shih
• Sherwin Tavakol
• Yinny Chan
• Fair Pisuttisarun
• Jingzhou Wang
• Joyce Tran
• Dennis Chang
• Matthew Nguyen
• Zanchen Li
• Michelle Song
• Eric Payson
• Guan Wang
• Frederick Hsu
• Austin Hoang
• Wesley Eastwood
• Lejun Huang
• Junsuke Nohara
• Hongsu Wang
• Harrison Khong
• Nicole Jacobs
• Bianca Yugar
• Laila Khorasani
• Serena Zhang
• Elijah Huang
• Karen Leung
• Hong-Ho Yang
• Rachel Hua
• Charles Lau
• Angela Sun
• Aaron Youn
• Lu Li
• Tecia Yang
• Michael Lugo
• Christine Xue
• Helen Han
• Samantha Dao
• Rachel Smith
• Emily Ketchum
• Rosa Nguyen
• Sarina Awatramani
• Yoon Lee
• Karen Xiao
• Matthew Kymn
• Ibrahim Malik
• Brian Chen
• Svasti Sharma
• Tianshu Bai
• George Vetushko
• Emilie Liu
• Giovanna Park
• Dora Duo
• Ashley Ma
• Lisa Ota
• Tiffany Fung
• Chris Rudewicz
• Aashi Patel
• Erica Chen
• Chelsea Jang
• Chris Qiu
• Rosemary Wang
• Rachel Wang
• Amy Zhang
• Daniel Vo
• Ada Chung
• Joy Youn
• Isabel Enriquez
• Lily Liu
• Chenshu Liu
• Yang (Frank) Dong
• Ilyass Majji
• Ke Huang
• Lucas Huang
• Ruochen (Tim) Li
• Courtney Situ