Zhefeng Guo, Ph.D.
he/him/his
2003 Ph.D. in Biochemistry, University of California, Los Angeles
1998 M.S. in Biochemistry, Peking University
1995 B.S. in Microbiology, Shandong University
Dr. Zhefeng Guo is a structural biologist and biochemist who joined the UCLA School of Medicine faculty in 2008. During his doctoral studies, he focused on developing electron paramagnetic resonance (EPR) methods to study protein structure, dynamics, and folding in Wayne Hubbell’s laboratory. In 2004, Dr. Guo joined David Eisenberg’s research group for postdoc training, working on the structural characterization of amyloid fibrils using the approaches of protein engineering and X-ray crystallography. His laboratory is currently investigating the structure and fibrillization mechanism of amyloid fibrils related to a wide range of human disorders such as Alzheimer’s, Parkinson’s and prion diseases, with the goal of developing molecular diagnostics and therapeutics for amyloid diseases.
Current Lab Members
Undergraduate Research Assistants
Diana Portugal
(she/her/hers)
Alumni
B.S. Molecular, Cell, &
Developmental Biology
Current Project(s):
Screening
Kestrel Locke
(she/her/hers)
Alumni
Psychology
Current Project(s):
Alpha-synuclein, Tau
Anson Cheung
(he/him/his)
Alumni
Biochemistry
Current Project(s):
DHFR, Tau
Zili Qiu
(he/him/his)
Fourth Year
Molecular, Cell, &
Developmental Biology
Current Project(s):
T4L, TMEM106B
Christine Ma
(she/her/hers)
Third Year
Molecular, Cell, &
Developmental Biology
(Specialization in Computing)
Current Project(s):
Screening, T4L
Mira Mehra
(she/her/hers)
Second Year
Neuroscience
Current Project(s):
Mutagenesis
Divya Hebber
(she/her/hers)
Third Year
Molecular, Cell, & Developmental Biology
Current Project(s):
DHFR
Caitlin Tang
(she/her/hers)
Third Year
Computational and Systems Biology
Current Project(s):
AD Biomarker and Sequencing
Elliana Tsang
(she/her/hers)
Third Year
Molecular, Cellular, & Developmental Biology
Current Project(s):
Yeast Prion
Lesly Leal
(she/her/hers)
Third Year
Molecular, Cell, &
Developmental Biology
Current Project(s):
AB aggregation and Screening
Nancy La
(she/her/hers)
Third Year
Molecular and Cellular Developmental Biology
Current Project(s):
Mutagenesis
Catrina Yang
(she/her/hers)
Second Year
Biology
Former Lab Members
Undergraduate Research Assistants
• Anna Li
• Josh Moore
• Wenshu (Claire) Zhang
• Allison Yoon
• Ani Oganesyan
• Chloe Wang
• Alex Sun
• James Zhen
• Brandon Dashtizad
• Katrina Cheng
• Andrew Tran
• Hyein (Haily) Kil
• Terri Shih
• Sherwin Tavakol
• Yinny Chan
• Fair Pisuttisarun
• Jingzhou Wang
• Joyce Tran
• Dennis Chang
• Matthew Nguyen
• Zanchen Li
• Michelle Song
• Eric Payson
• Ellie Hilgert
• Eliot Mark
• Guan Wang
• Frederick Hsu
• Austin Hoang
• Wesley Eastwood
• Lejun Huang
• Junsuke Nohara
• Hongsu Wang
• Harrison Khong
• Nicole Jacobs
• Bianca Yugar
• Laila Khorasani
• Serena Zhang
• Elijah Huang
• Karen Leung
• Hong-Ho Yang
• Rachel Hua
• Charles Lau
• Angela Sun
• Aaron Youn
• Lu Li
• Tecia Yang
• David Reynolds
• Michael Lugo
• Christine Xue
• Helen Han
• Samantha Dao
• Rachel Smith
• Emily Ketchum
• Rosa Nguyen
• Sarina Awatramani
• Yoon Lee
• Karen Xiao
• Matthew Kymn
• Ibrahim Malik
• Brian Chen
• Svasti Sharma
• Tianshu Bai
• George Vetushko
• Emilie Liu
• Giovanna Park
• Dora Duo
• Ashley Ma
• Lisa Ota
• Tiffany Fung
• Chris Rudewicz
• Aashi Patel
• Erica Chen
• Chelsea Jang
• Chris Qiu
• Rosemary Wang
• Rachel Wang
• Amy Zhang
• Daniel Vo
• Ada Chung
• Joy Youn
• Isabel Enriquez
• Lily Liu
• Chenshu Liu
• Yang (Frank) Dong
• Ilyass Majji
• Ke Huang
• Lucas Huang
• Ruochen (Tim) Li
• Courtney Situ